Enovid Covid Nasal Spray Review

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12/29/22 Update: A retailer we've purchased from, IsraelPharm, is offering 10% off 3 boxes of Enovid through 12/31/22. We have no connection with the company other than as a customer.

Our Enovid Covid nasal spray review is based on our use of the product over the past month, both in the U.S. and while traveling in Europe. As we wrote in Where are the COVID-19 Nasal Sprays, there's a gap in the tool arsenal against Covid-19 that we have available in the U.S. This might sound odd, since we've had face masks since early in the pandemic, then mRNA vaccines that are highly effective against serious illness and death, and now Paxlovid as an oral antiviral medication to be taken within five days of developing symptoms. But the gap is prophylactic, since sometimes it's not possible to wear an N95 or KF94 face mask in all situations, for example a long plane flight or time in an airport, when you need to drink or eat something. Enter the Enovid nasal spray made in Israel and invented by Canadian company SaNOtize, which uses nitric oxide to destroy the virus and prevent viral replication.

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Buying Enovid

We bought our vials of Enovid from Israel Pharm, which charges $45 per 25 ml. bottle (free shipping when buying at least two bottles). At time of writing, Enovid is back in stock, with the current expiration date of October 6, 2023. Each bottle is said to contain a 1 month supply, and that was accurate for us when using as directed, spraying twice in each nostril twice a day. The shipment took about one week to reach us from Israel.

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Using Enovid

I won't pretend that it's very pleasant using the product, as there's a slight stinging sensation when using as directed (slightly inhaling when spraying each nostril). The stinging is temporary, just for a few seconds. Our son doesn't like it, although he tolerates it.

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So Far COVID Negative

While it could be luck, we've remained negative for Covid while using the product, even while in Denmark, where we did have some meals indoors and were in relatively crowded areas such as Tivoli. No one in Denmark, apart from a few foreigners, was wearing face masks during our visit. We were especially focused on not becoming infected with Covid because our son had to test negative before attending a summer camp, which he did. We can't prove it, but we suspect our family's use of Enovid helped his odds.

If you've used Enovid or another COVID-19 nasal spray, what was your experience?

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Suzanne
Suzanne
1 year ago

We’re cautiously optimistic about Enovid! Trying it out for some riskier activities (we’re still quite cautious but want our kids to have birthday parties, play sports, etc.) at home and then looking to use it as a tool to re-enter the world of international travel. Do you mind if I ask what your regimen is/was? Did you vary your dosing for home vs. abroad?

Mz W
Mz W
1 year ago

The instructions say 5x a day if you’ve been exposed. But it doesn’t say how many days people would have to continue taking it 5x a day. Do you know? Wondering about using it when I have doctor’s appointments…

Gigi
Gigi
1 year ago

I’ve been considering using it for my kiddo but feel nervous. US pediatrician had of course never heard of it. Can I ask about your decision making process on using it for kids, as instructions say for 13 and up? I so desperately want to keep my kiddo protected during this upcoming school year in the midst of viral blizzard! Thank you 🙏

Gigi
Gigi
1 year ago

Thank you for this info! It’s so hard to make the best choices to protect our kids, so I do appreciate your insight!

luanne
luanne
1 year ago

Hi Hilary,

I wondered if an adult could use this and Paxlovid (if Covid+) simultaneously?

Andrea Grande
Andrea Grande
1 year ago

Do you think It is dangerous to use a new bottle beyond the expiration date of 1 month?

Gina Carrano
Gina Carrano
1 year ago

Thanks so much for that info – I was surfing the web trying to find this out, as I have one I opened about 6 weeks ago for a big wedding that I was in, and want to use it again before visiting with some older family members. I have thus far only used it when I’m going to be around a lot of people (which I’m usually not) so I still have a lot left from my first bottle, and would hate to waste it and open my 2nd (I bought a 2pack) if the original is still good.

Bob
Bob
1 year ago
Reply to  Andrea Grande

Sanotize recently increased open bottle life from 30 to 60 days, and unopened bottle shelf life to 24 months. It’s on their FAQ.

Debra
Debra
7 months ago

How long before a PCR would you “pause” your Enovid doses to guarantee accuracy? (This is after a known exposure unfortunately 🙁

Theresa
Theresa
6 months ago

I guess if you do a mouth swab as well as the nasal, you might still pick up a positive result?

L.perdue
L.perdue
1 year ago

Does anyone know how well this works against the Ba.4 and five variants?

Scottee Meade
Scottee Meade
1 year ago

Does the free shipping apply internationally, like to the US? The pharmacy requires an ID number, such as SSN, Medicare, passport, drivers license. That doesn’t sound safe to me. Is it?

Tom Tyndal
Tom Tyndal
1 year ago

Was delivery fast. We live in Australia, have just placed an order. We cruise in 17 days time.

Helene So
Helene So
1 year ago
Reply to  Tom Tyndal

was super quick for me (melb). I think 5 days? Couldn’t believe it, actually.

Jon
Jon
1 year ago

I’ve used it prophylactically for a year after my first infection. So far no second infection. I am worried about repeated use of this however because I notice that sometimes after I spray, it makes me cough. So maybe its going into the lungs? I’m no doctor but i’m not sure if spraying something in your nose everyday can cause lung damage? Enovid themselves say its safe to use daily.

gudwin
gudwin
1 year ago

I used this when I had covid over xmas. My symtoms(headache) did go away the same day I used it. I then used as directed 5 times a day for 10 days. I was still testing positive after 10 days, but I hardly had any symptoms through the whole time I used it, just a runny nose sometimes and cough now and again. I was unvaccinated and it was the first time I had caught covid so I have no idea if it made much difference, as I am in a low risk category. I would probably not take it… Read more »

Shelley
Shelley
7 months ago

My family has used Enovid for the past 2 years, and it has been very effective in warding off viral infections. When necessary, especially during travel we’ve used the spray 2-3 times per day. Enovid does a wonderful job of reducing if not eliminating covid viral loads and we would highly recommend this product.

Lisa
Lisa
6 months ago
Reply to  Shelley

Hello, I purchased Enovid but my husband is concerned with side effects. Has anyone experienced any side effects that would deter you from using this product. T

Lisa
Lisa
6 months ago

Hello!
I replied to one specific person by mistake.
I would love any feedback on side effects from this Enovid. I am excited to have it on hand but my husband is concerned because he has read about possible side effects. Does anyone have anything to share either way?
Thank you so much,
Lisa

Lisa
Lisa
6 months ago

Thank you, Hilary. I appreciate the feedback and information. I am also curious…do you each have your own bottle or can a bottle be shared by more than one person?